Guido Winkmann| 21 |  | Karius | |||
| 18 |  | Brosinski | |||
| 16 |  | Bell | |||
| 24 |  | Park | |||
| 20 |  | Júnior Díaz | |||
| 15 |  | De Blasis | 66 | ||
| 13 |  | Koo | 78 90 | ||
| 11 |  | Mallı | 89 | ||
| 14 |  | Baumgartlinger | 81 | ||
| 6 |  | Geis | |||
| 23 |  | Okazaki |
| 1 |  | Leno | |||
| 13 |  | Hilbert | |||
| 21 |  | Toprak | |||
| 16 |  | Jedvaj | 35 | ||
| 18 |  | Wendell | 29 | ||
| 8 |  | Bender | |||
| 27 |  | Gonzalo Castro | |||
| 10 |  | Çalhanoğlu | 86 | 73 | |
| 7 |  | Son | 15 | ||
| 38 |  | Bellarabi | 45 | ||
| 11 |  | Kießling | 78 | 59 |
Substitutes
Managers
Milestones
Match #300 of Mainz 05 in Bundesliga
Match #100 of Koo in Bundesliga
Doublet #1 of Koo in Bundesliga
Goal #48500 in Bundesliga (Min 73)