Competition
Round
Stadium
Date
Sunday 26/09/2021
Andy MadleyCompetition
Round
Stadium
Date
Sunday 26/09/2021
| 1 |  | McCarthy | |||
| 21 |  | Livramento | |||
| 22 |  | Salisu | |||
| 35 |  | Bednarek | |||
| 2 |  | Walker-Peters | 74 | ||
| 8 |  | Ward-Prowse | |||
| 6 |  | Romeu | |||
| 10 |  | Adams | 64 | ||
| 9 |  | Armstrong | |||
| 24 |  | Elyounoussi | |||
| 11 |  | Redmond | 64 |
| 1 |  | José Sá | |||
| 22 |  | Semedo | 87 | ||
| 27 |  | Saïss | |||
| 23 |  | Kilman | |||
| 16 |  | Coady | |||
| 5 |  | Marçal | |||
| 28 |  | Moutinho | |||
| 32 |  | Dendoncker | |||
| 10 |  | Daniel Podence | 71 | ||
| 9 |  | Raúl Jiménez | 61 | ||
| 26 |  | Hwang | 88 |
Substitutes
| 2 |  | Hoever | 87 | ||
| 37 |  | Adama | 71 | ||
| 8 |  | Rúben Neves | 88 | ||
| 11 |  | Trincão | |||
| 15 |  | Boly | |||
| 21 |  | Ruddy | |||
| 17 |  | Fábio Silva | |||
| 13 |  | Moulden | |||
| 39 |  | Cundle |
Managers
Milestones
Match #50 of Djénépo in Premier League (all with club Southampton)