Marco Guida| 25 |  | Reina | |||
| 77 |  | Marušić | |||
| 3 |  | Luiz Felipe | |||
| 33 |  | Acerbi | |||
| 23 |  | Hysaj | |||
| 21 |  | Milinković-Savić | 10 | ||
| 10 |  | Luis Alberto | 66 | ||
| 6 |  | Lucas Leiva | 60 | 24 | |
| 7 |  | Felipe Anderson | 62 | ||
| 9 |  | Pedro | 19 | ||
| 17 |  | Immobile | 90 |
| 1 |  | Rui Patrício | 11 | ||
| 2 |  | Karsdorp | 82 | ||
| 3 |  | Ibáñez | 41 | ||
| 23 |  | Mancini | |||
| 5 |  | Viña | 82 | 48 | |
| 4 |  | Cristante | 45+1 | ||
| 17 |  | Veretout | 87 69 | ||
| 77 |  | Mkhitaryan | |||
| 92 |  | El Shaarawy | 64 | ||
| 22 |  | Zaniolo | 77 | ||
| 9 |  | Abraham |
Substitutes
| 32 |  | Cataldi | 60 | 87 | |
| 8 |  | Akpa-Akpro | 66 | ||
| 94 |  | Muriqi | 90 | ||
| 26 |  | Radu | |||
| 27 |  | Moro | |||
| 18 |  | Luka Romero | |||
| 31 |  | Adamonis | |||
| 1 |  | Strakosha | |||
| 88 |  | Bašić | |||
| 5 |  | Escalante | |||
| 29 |  | Lazzari | |||
| 4 |  | Patric |
| 59 |  | Zalewski | 82 | ||
| 6 |  | Smalling | 82 | ||
| 11 |  | Carles Pérez | 77 | ||
| 14 |  | Shomurodov | 64 | ||
| 52 |  | Bove | |||
| 13 |  | Calafiori | |||
| 63 |  | Boer | |||
| 55 |  | Darboe | |||
| 24 |  | Kumbulla | |||
| 87 |  | Fuzato | |||
| 21 |  | Mayoral | |||
| 42 |  | Diawara |
Managers
Milestones
Match #200 of Milinković-Savić in Serie A (all with club Lazio)
Goal #1 of Pedro in Serie A with club Lazio
Goal #1 of Ibáñez in Serie A