Marco Di Bello| 25 |  | Ospina | |||
| 22 |  | Di Lorenzo | |||
| 26 |  | Koulibaly | |||
| 44 |  | Manolas | |||
| 23 |  | Hysaj | |||
| 8 |  | Fabián | 83 | ||
| 5 |  | Bakayoko | 75 | ||
| 11 |  | Lozano | 79 23 27 | ||
| 21 |  | Politano | 61 | 30 | |
| 14 |  | Mertens | 75 | ||
| 9 |  | Osimhen | 83 | 43 |
| 57 |  | Sportiello | |||
| 27 |  | Depaoli | |||
| 17 |  | Romero | |||
| 6 |  | Palomino | 46 | ||
| 2 |  | Tolói | 38 | ||
| 8 |  | Gosens | 81 | 45+1 | |
| 88 |  | Pašalić | |||
| 15 |  | De Roon | |||
| 10 |  | Papu Gómez | 55 | ||
| 72 |  | Iličić | 63 | ||
| 91 |  | Zapata | 46 |
Substitutes
| 2 |  | Malcuit | 75 | ||
| 4 |  | Demme | 83 | ||
| 68 |  | Lobotka | 75 | ||
| 31 |  | Ghoulam | 61 | ||
| 37 |  | Petagna | 83 | ||
| 33 |  | Rrahmani | |||
| 16 |  | Contini | |||
| 6 |  | Mário Rui | |||
| 18 |  | Llorente | |||
| 19 |  | Maksimović | |||
| 1 |  | Meret |
| 19 |  | Djimsiti | 46 | 81 | |
| 9 |  | Muriel | 81 | ||
| 7 |  | Lammers | 55 | 69 | |
| 18 |  | Malinovskyi | 63 | ||
| 26 |  | Mojica | 46 | ||
| 1 |  | Radunović | |||
| 11 |  | Freuler | |||
| 33 |  | Hateboer | |||
| 59 |  | Miranchuk | |||
| 4 |  | Šutalo | |||
| 31 |  | Rossi |
Managers
Milestones
Match #1 of Bakayoko in Serie A with club Napoli
Goal #1 of Osimhen in Serie A
Match #1 of Depaoli in Serie A with club Atalanta
Match #200 of Zapata in Serie A