Robert Jones| 24 |  | Onana | |||
| 3 |  | Mazraoui | |||
| 6 |  | Lisandro Martínez | 90+3 | ||
| 4 |  | De Ligt | |||
| 20 |  | Dalot | 45+1 | ||
| 25 |  | Ugarte | 84 | 42 | |
| 8 |  | Bruno Fernandes | 70 | ||
| 18 |  | Casemiro | 85 | ||
| 17 |  | Garnacho | |||
| 10 |  | Rashford | 73 | 67 | |
| 9 |  | Højlund | 84 |
| 1 |  | Sánchez | |||
| 27 |  | Gusto | 46 | 36 | |
| 24 |  | James | |||
| 6 |  | Colwill | |||
| 29 |  | Fofana | |||
| 45 |  | Lavia | 71 | ||
| 25 |  | Caicedo | 74 | ||
| 20 |  | Palmer | |||
| 15 |  | Jackson | 90+4 | ||
| 11 |  | Madueke | 71 | ||
| 7 |  | Pedro Neto |
Substitutes
| 3 |  | Cucurella | 46 | ||
| 8 |  | Enzo Fernández | 71 | ||
| 10 |  | Mudryk | 71 | ||
| 4 |  | Adarabioyo | |||
| 18 |  | Nkunku | |||
| 12 |  | Jörgensen | |||
| 14 |  | João Félix | |||
| 40 |  | Renato Veiga | |||
| 5 |  | Badiashile |
Managers
Milestones
Match #27000 in Premier League
Match #50 of Colwill in Premier League
Match #1 of Van Nistelrooy in Premier League